Available online: http://www.ifraorg.org/en-us/ingredients#.V8nKn-krKUk Accessed September 2016. Some of these chemicals are defined as priority pollutants, which are regulated by governmental agencies because of their toxicity or persistence in organisms and food webs. Occupational studies indicate styrene is ototoxic in humans, as exhibited by increases in hearing thresholds at high sound frequencies, although there are uncertainties regarding the dose-response (threshold) relationship and the impact of co-exposure to noise. Available online: http://www.epa. HEALTH CONCERNS: Styrene acrylates copolymer is considered safe because there is a low likelihood of absorption of the full compound. It dissolves in some liquids but doesn't dissolve easily in water. An example is the 2019 explosion of the tanker Stolt Groenland; in this incident 5,250 metric tons of styren… There are no strong or consistent indications that styrene causes any form of cancer in humans. It is the mucous membrane that is mainly affected by exposure to styrene gas. Long-term exposure to styrene in humans results in effects on the central nervous system (CNS), such as headache, fatigue, weakness, and depression, CSN dysfunction, hearing loss, and nerve damage. Ingredients. Available online: http://www.atsdr.cdc.gov/toxfaqs/TF.asp?id=420&tid=74,  Engel C, Nudelman MA, Rasanayagam S, Witte M. Pretty Scary 2 Unmasking toxic chemicals in kids’ makeup.  CIR (Cosmetic Ingredient Review). 41.1.1 Historical Background. A father rushes to take his child for treatment at King George Hospital.  Weiderpass E, Pukkala E, Kauppinen T, Mutanen P, Paakkulainen H, Vasama‐Neuvonen K, Boffetta P, Partanen T. Breast cancer and occupational exposures in women in Finland. Inhalation of styrene following a single exposure can lead to irritation of the mucous membranes of the nose and throat, increased nasal secretion, wheezing and coughing. The potential for styrene to produce effects on the endocrine system, specifically on (anti)estrogenic, (anti)androgenic, thyroid, and prolactin activities has been the subject of a number of studies. 400 E Joppa Road, Suite 108 Studies of general population environmental and consumer styrene exposure and cancer are less informative than the worker studies, but the available evidence does not suggest these low exposures are a concern. Much of this information, however, cannot be meaningfully interpreted given limitations in study design, population heterogeneity, potential co-exposures to other genotoxic substances, and in the styrene exposure information. Indicator tests detecting sister chromatid (SCE), DNA strand breaks, DNA methylation, and DNA adducts have also produced variable results for styrene. 2014. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. Even in trace amounts it is concerning to have the presence of a carcinogen in products marketed to children and adults. Error: (#10) This endpoint requires the 'manage_pages' or 'pages_read_user_content' permission or the 'Page Public Content Access' feature.  EPA: Environmental Protection Agency. WHAT IS STYRENE ACRYLATES COPOLYMER: Styrene acrylates copolymer is a chain of polymers consisting of styrene and acrylate which is added to cosmetics for color. Ethenyl benzene, Phenylethylene, Styrene monomer, Styrol, Vinyl benzene Colorless to yellow, oily liquid with a sweet, floral odor. Styrene. These workplace studies have found limited evidence of an association between occupational exposure to styrene and human cancer. It is a flammable liquid that is used in the manufacturing of polystyrene plastics, fiberglass, rubber, and latex. Rats have less of a comparable lung enzyme, CYP2F4, than mice, produce less ring-oxidized metabolites, and are demonstrated to have no cytotoxic, proliferative, or tumorigenic lung changes at high exposures (up to 1000 ppm) for two years. Endocrine Disruption: The European Commission on Endocrine Disruption classifies styrene as a Category 1 endocrine disruptor, meaning evidence for endocrine disruption has been documented in humans and wildlife. 2014. There are many studies that have examined the genotoxic potential of styrene in styrene exposed workers. Styrene, like many volatile hydrocarbon chemicals, can cause mild and reversible nervous system effects if workplace exposures are not controlled. Five of the mouse studies found increases in lung tumors identified as bronchoalveolar adenomas or adenocarcinomas. Styrene is a colorless, flammable liquid, which has a sweet odor and is highly volatile. 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